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The Effects of Oral Sprays Containing Prunus mune Extract and Natural Substances on Halitosis

International Journal of Clinical Preventive Dentistry 2015³â 11±Ç 3È£ p.191 ~ 198
Hyun Yong-Cheol, ¹ÚÁ¤Àº, ±ÇÇÏÁ¤, ÀåÁ¾È­, ¾ç´Þ´Ô, Ȳ¼ö¿¬, ±è¹Ì¿¬, ¹Ú¿ë´ö, Ȳ°æ¼÷,
¼Ò¼Ó »ó¼¼Á¤º¸
 ( Hyun Yong-Cheol ) - Kyung Hee University School of Dentistry Department of Preventive and Social Dentistry
¹ÚÁ¤Àº ( Park Jung-Eun ) - Kyung Hee University School of Dentistry Department of Preventive and Social Dentistry
±ÇÇÏÁ¤ ( Kwon Ha-Jeong ) - Kyung Hee University School of Dentistry Department of Preventive and Social Dentistry
ÀåÁ¾È­ ( Jang Jong-Hwa ) - Hanseo University Department of Dental Hygien Science
¾ç´Þ´Ô ( Yang Dal-Nim ) - Kyung Hee University School of Dentistry Department of Preventive and Social Dentistry
Ȳ¼ö¿¬ ( Hwang Su-Yeon ) - Kyung Hee University School of Dentistry Department of Preventive and Social Dentistry
±è¹Ì¿¬ ( Kim Mi-Yeon ) - Kyung Hee University School of Dentistry Department of Preventive and Social Dentistry
¹Ú¿ë´ö ( Park Yong-Duk ) - Kyung Hee University School of Dentistry Department of Preventive and Social Dentistry
Ȳ°æ¼÷ ( Hwang Kyung-Sook ) - Shinhan University Department of Dental Technology

Abstract


Objective: The purpose of this study is to evaluate the inhibition effects of Prunus mune extract (PME) their mixtures containing green tea extract (GTE) (PME+GTE), Zanthoxylum schinifolium extract (ZCE) (PME+ZCE) on the volatile sulfur compounds (VSCs) oral pathogenicity microorganisms.

Methods: The amount of the VSCs and oral microorganism in the mouth of fifteen volunteers who healthy Koreans were measured by Sensor Gas Chromatograph ODSA-P2 (FIS Inc., Hyogo, Japan) and real-time polymerase chain reaction, respectively.

Results: The average concentration of oral VSCs was lower in the PME+GTE and PME+ZCE group, especially, the VSCs in PME+ZEC group was statistically decreased compared to the control group. Among the oral bacteria, Tannerella forsythia was not detected in PME, PME+GTE group after 2 weeks, and Prevotella intermedia was significantly inhibited in each group.

Conclusion: All experimental sample showed the inhibition effects on the oral VSCs, the cause of halitosis, especially, the inhibition effect of PME£«GTE and PME£«ZCE groups were higher than PME group.

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prunus mune; green tea; zanthoxylum schinifolium; halitosis; oral sprays

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